Let’s Talk ADHD: Treatment Options

Traditional and functional medicine both treat ADHD with various methods. Stimulant medication, behavior and dietary interventions, and even supplementation can be helpful in treating ADHD. It's important to remember that there is no one-size-fits-all when it comes to treatment; it depends on the individual and their specific case. Read on for some different options to be considered in treatment. Not sure if it's ADHD? Read Part 1 for an overview of the different types and symptoms.

In traditional Western medicine, stimulant medication is typically the first line of treatment for ADHD. Popular stimulant medications (some which may sound familiar) include Ritalin/Concerta (methylphenidate) and Adderall/Adderall XR (amphetamine salts). Treatment with medication is dependent on a number of factors, primarily: age, symptoms, comorbid (co-existing) conditions, as well as parental comfort with the use of medication. For children ages 4 to 6, behavioral interventions are preferred over medication use.

In functional and integrative medicine, ADHD treatment options primarily focus on healing the body by establishing positive lifestyle habits and supporting healthy brain function.

"Integrative medicine incorporates evidence-based medicine, both conventional and complementary and alternative therapies, to deliver personalized care to the patient, emphasizing diet, nutrients, gut health, and environmental influences as a means to decrease symptoms associated with chronic disorders." (Esparham, 2014)

Behavioral interventions, improved diet, nutrient supplementation, better sleep, and increased physical activity have all been shown to have beneficial effects either alone or in combination with medication use.

What is a neurotransmitter and why are they important?

Neurotransmitters are known as chemical messengers in the body. They transmit information within the nervous system and enable the brain to perform a variety of functions.

ADHD involves differences in how the brain regulates certain neurotransmitters, particularly dopamine and norepinephrine. Functional medicine looks at the factors that can support healthy neurotransmitter function, such as nutrition, sleep, gut health, and physical activity, and builds them into the treatment plan.

Behavioral Interventions

Modifying children's physical and social environments by using rewards and non-punitive consequences can help manage ADHD. Some effective strategies include:

• Maintaining a daily schedule
• Providing specific and logical places to keep schoolwork, toys, clothes, etc.
• Keeping distractions to a minimum (e.g., putting phone in a different room when doing schoolwork)
• Using charts and checklists to help stay on task
• Setting small, reachable goals
• Limiting choices
• Rewarding positive behavior
• Using calm discipline (e.g., "time out," distraction, removing child from situation)
• Finding activities in which the child can be successful (hobbies/sports)

Dietary Interventions

What we eat has a profound effect on our health. "Nutritional deficiencies from a 'Western' diet, food insecurities, artificial food additives and dyes, food sensitivities and allergies have all been implicated in ADHD." (Esparham, 2014) Research has also linked oxidative stress and inflammation with ADHD. Since Western diets are typically high in omega-6 fatty acids, sodium, and sugar, all of which can induce inflammation, swapping out processed foods with more whole foods (especially plants) may help decrease ADHD symptoms.

Gluten-related disorders (Celiac Disease and non-celiac gluten sensitivity) may also be associated with ADHD. Exposure to gluten in these individuals can cause intestinal damage that can lead to chronic inflammatory immune dysregulation throughout the body. In some people, this chronic inflammation masquerades as behavioral and psychiatric disorders, such as ADHD. For these individuals, eliminating gluten can improve mood, focus and attention, as well as decrease disruptive behaviors.

Nutrient Supplementation

Adequate nutrient levels play a large role in optimizing neurotransmitters and brain activity. Below is a list of various nutrients that may affect ADHD:

• Micronutrients play a large role in metabolism, neurotransmission, cognitive function, immune function, and detoxification. Some of the important micronutrients, in relation to ADHD, include Zinc, Iron, Vitamin B6, Magnesium, Polyunsaturated Fatty Acids (PUFAs)/Omegas, and Vitamin D.
• Zinc is a micronutrient that participates in the metabolism of neurotransmitters, hormones, and nutrients, and supports proper immune function. Our brains also need zinc to form neural pathways, so a zinc deficiency can have a significant impact on attention, motor activity, cognition, and behavior.
• Iron is a key player in neurotransmitter metabolism. Because neurotransmitter dysregulation is often implicated in ADHD, it is logical to suggest that iron dysregulation can be implicated in some cases of ADHD. In addition, excess inflammation and low levels of glutathione (the body's main detoxifier and antioxidant) can result in iron dysregulation.
• Vitamin B6: Insufficient Vitamin B6 affects metabolism of polyunsaturated fatty acids, hemoglobin synthesis, and neurotransmission. B6 is also a cofactor in the metabolism of neurotransmitters including serotonin, glutamate/GABA, and dopamine (inappropriate levels have all been implicated in ADHD). By regulating neurotransmission, vitamin B6 may improve executive function and symptoms of ADHD.
• Magnesium acts as a protectant to the nervous system when there are excessive excitatory neurotransmitters, such as glutamate. Appropriate magnesium supplementation may be a useful adjunct for children on stimulant medication.
• Polyunsaturated fatty acids (PUFAs): disturbances in PUFAs have also been implicated in ADHD, as they are necessary for neuronal function to support neurotransmission. The typical American diet has an imbalance of omega-6 and omega-3 PUFAs; an elevated omega-6 is implicated in inflammation. DHA (an omega-3) is essential in neurocognitive development of children.
• Vitamin D is essential for normal brain development and regulates two different parts of the immune system by enhancing protective mechanisms against inflammation.
• Probiotics and probiotic foods (kimchi, sauerkraut, yogurt, kombucha in moderation) have been shown to promote a healthy gut. We talk a lot about the importance of the gut microbiome because research has shown that there is a gut-brain-body continuum. The gut has its own nervous system, and gut bacteria produce compounds that send signals to the brain and can impact mood and behavior.

Better Sleep

It is also important to recognize the effect of sleep on the body. Healthy, deep/REM sleep is essential for the body to "reset" at night, both physically and mentally. This is the time for your neuroendocrine system to "catch up" with the day and prepare for the day ahead. Should there be a disruption in sleep cycles, there will be a consequential disruption in neuroendocrine function the next day. This could be as simple as feeling sluggish and having brain fog the next day, all the way to a child having a meltdown in school. It has been shown that treatment of sleep problems may improve ADHD symptoms. Ironically, some of the stimulant medications used to treat ADHD can exacerbate some sleep issues, so it's important to take that into consideration when discussing a treatment plan.

Physical Activity

Regular exercise is important not only for overall health, but also for brain health. Ever heard of "runner's high"? This is a release of neurotransmitters to the brain and body that help to create a positive mood. It has been shown that 30-60 minutes of vigorous activity a day has a positive effect on ADHD, especially for those with the hyperactive/impulsive type. Furthermore, studies have shown that physical activity specifically in the morning can have a positive effect on attention and behavior throughout the day.

Treating ADHD is an individual thing

It cannot be stressed enough that there are many ways to attempt treating ADHD, and there generally is not just "one way" to do so. Finding a qualified professional, asking the right questions, doing adequate testing and trying different solutions can absolutely yield positive results. While medication is an option, remember that it's not the only option available.

Originally published September 2021. Updated November 2, 2026.

References

1. Esparham A, Evans RG, Wagner LE, Drisko JA. Pediatric Integrative Medicine Approaches to Attention Deficit Hyperactivity Disorder (ADHD). Children, 2014.